Science and Technology links (April 29th, 2018)

  1. Our heart regenerates very poorly. That is why many of us will die of a heart condition. Harvard researchers find the mice that exercise generate many more new heart cells. The researchers hint at the fact that you might be able to rejuvenate your heart by exercising.
  2. Cable TV is losing subscribers faster than anticipated. In related news, cable prices are rising at 4 times the rate of inflation. That is, just as cable TV is facing stiffer competition from Netflix and others, it is also raising its prices.
  3. The rich get richer while the poor get poorer. That’s called the Matthew effect. It exists in science: young scientists who get lucky early on tend to do much better funding-wise. But why is that? It seems to be mostly because people who get bad news early on give up or become less aggressive:

    Our results show that winners just above the funding threshold accumulate more than twice as much funding during the subsequent eight years as nonwinners with near-identical review scores that fall just below the threshold. This effect is partly caused by nonwinners ceasing to compete for other funding opportunities, revealing a participation mechanism driving the Matthew effect.

    It follows that a key to success is to take failure well. It is like a superpower.

  4. A dietary supplement, MitoQ, is believed to rejuvenate blood vessels in mice. A new study finds that the effect is similar in human beings. (I am not taking this supplement.)
  5. When health workers go on strike, mortality stays level or decrease.
  6. Student strikes negatively affect performance on mathematics tests, but not on language tests.
  7. Naked mole rats do not age biologically. That is, their mortality rate does not increase with age. It is a rather unique feature among mammals and we do not know exactly what makes it work. Lewis et al. found that naked mole rats have relatively low levels of some amino acids in their blood, levels resembling those of hibernating quirrels.
  8. Should you be eating more fibers? Maybe not:

    increasing fibre in a Western diet for two to eight years did not lower the risk of bowel cancer (…) after four years participants receiving dietary fibre had higher rates of bowel cancer.

    In concrete terms, this makes me question the belief that whole wheat bread is better for your health than white bread.

  9. It seems that Neandertals had boats of some sort, going from island to island in the Mediterranean.
  10. Years ago I produced a small podcast for my students, in the pre-iPhone era. Feedback from my students was not great: they complained that they simply did not have time for such things. I used to listen to podcasts myself, but the hassle of selecting, downloading and managing audio files was too annoying. I had since assumed that podcasts had gone out of favor. I have recently rediscovered podcasts. Apple reports having half a million shows on offer, and they have counted 50 billion downloads. It seems that podcasts are all the rage right now. I suspect that this has to do with the high quality of cellular network connections. I can listen to podcasts down in Montreal’s subways. Though the monthly fees for my smartphone are high, the service is great… usually superior to what I get with wifi at the office. This almost makes me want to resume my own podcasting, but I’d have to give up other activities to make time.
  11. Progeria is a terrible disease that appears like accelerated aging. Many kids suffering from progeria won’t live to become adults. In a small trial, a protein inhibitor was found to drastically reduce the mortality rate of patients affected with progeria. Is a cure on the way?
  12. My colleagues from other scientific fields often assume that software is just a form of applied mathematics. Surely we can automatically reason over software implementations and prove them to be correct. This turns out to be remarkably difficult. It is hard to prove as correct even silly small functions, to say nothing of actual software. The fact is, building software is very much an empirical endeavour… which is why people like me always spend at least as much time testing the software as writing it. Moreover, I always assume that my software is, at best, empirically correct. There are always cases where it will fail, even if the hardware runs perfectly (which it does not).Hillel Wayne checks whether a particular programming style that is fashionable right now (functional programming) makes software correctness easier to verify. He finds the evidence weak. To me, the real take-away should be that it is ridiculously hard to prove that code is real-world correct, irrespective of the programming style.

    What is also interesting is the reaction of the functional-programming community to his analysis…

    A common critique of functional-programming communities is they have very aggressive people and this held true here.

    I have been on the receiving end of the functional-programming communities. A mere joke at functional programming expense is enough to get hate mail. That is, software is nothing like objective truth and pure ideas. It is filled with deeply held ideologies.

  13. In our society is widely accepted that men are freer than women sexually, even though we have contraception that should act as an equalizer. That is, a woman that openly likes sex is a “slut” or a “prostitute” whereas a men that likes sex merely has a healthy libido. People who care about gender fairness should be concerned with this obvious bias. But what is the cause? Baumeister and Twenge find that the view that men suppress female sexuality is flatly contradicted and the the evidence favors the view that women have worked to stifle each other’s sexuality because sex is a limited resource that women use to negotiate with men, and scarcity gives women an advantage.

Daniel Lemire, "Science and Technology links (April 29th, 2018)," in Daniel Lemire's blog, April 29, 2018.

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Daniel Lemire

A computer science professor at the University of Quebec (TELUQ).

12 thoughts on “Science and Technology links (April 29th, 2018)”

  1. re. Software reliability:
    IMHO the purported better reliability of functional software is an artifact of “selection”, being more difficult to begin with functional software is practiced by smarter people thus ensuring better results.
    I think the same occurred with objects languages.
    Alas, with time the new technology becomes less intimidating, the usual morons encroach the field and the niceness falters…

  2. I don’t eat whole wheat bread because of fibre (which I always believed was a fad). I eat it because it tastes better (it tastes of something, which that pre-sliced blotting paper does not).

  3. Regarding the fiber study, the study clearly states:

    “The quality of evidence was low. The high risk of bias of included studies, small sample size, large number of missing data and the use of indirect measures gave us little confidence on the findings of this review.”

    If the authors have little confidence in the conclusions, then so do I.

    (Incidentally, I take high fiber foods to avoid hemorrhoids – did not even know about bowel cancer).

    Finally, in the US, there’s no good correlation that wheat bread has more fiber than white bread. I assiduously check the nutrition information and most of the wheat bread in the general supermarket had negligible fiber. I have to hunt to find bread that has significant fiber (e.g. 3g or more per slice).

    1. If the authors have little confidence in the conclusions, then so do I.

      This is a meta-review. What they are effectively saying is that there is lack of evidence.

      (Incidentally, I take high fiber foods to avoid hemorrhoids – did not even know about bowel cancer).

      Is there evidence that high fiber foods prevent hemorrhoids? That is, that long-term consumption of fiber makes you less likely to suffer from hemorrhoids?

      Please take into account that reducing dietary fiber intake reduces constipation. And chronic constipation is a risk factor for hemorrhoids.

      1. Hi Daniel,

        Sorry I did not reply earlier – I was expecting email notification if someone responded.

        Regarding the fiber study, I stand corrected.

        Regarding fiber and constipation, my understanding is that it is actually a lack of water intake along with the fiber (or so my doctor told me). The water softens up the fiber. In fact, a lot of fiber+water can lead to diarrhea.

        Regarding fiber and hemorrhoids, it’s not the fiber per se that helps. It is the straining during constipation that creates them. As for research on it, I’ll have to check. There are various causes of hemorrhoids, though – and straining is only one of them. I would imagine if there are other reasons one is getting them, fiber may not help.

        I know it is not evidence, and only an anecdote, but: I used to have hemorrhoid issues. My fiber intake was probably a fifth of the recommended amount. Once I increased it significantly, I stopped suffering from them.

  4. As for podcasts, if you have a smartphone, check out the PocketCasts App (not free, but worth it). It will let you subscribe and download in advance (where you have Wifi), so you can listen without incurring data costs. For me it’s a must for every road trip.

      1. The practical difficulty of pre-downloading podcasts is that podcasts appear on a daily basis.

        If you actually want them on a daily basis, PocketCasts can be set to download them automatically for you when connected to Wifi. I don’t know if they have features like expiration, etc. I only download when I go on road trips.

  5. “It follows that a key to success is to take failure well.”

    Yes, but this is trickier than merely always pressing on in the face of negative outcomes. For instance, how many of the borderline scientists who received bad news early on, and left academia as a consequence, became happier with their lives than the borderline scientists who remained? How many of them arguably contributed more to society in their new career than they did in their old one?

    These numbers are difficult to estimate, of course, and it is even more difficult to reach agreement with others on such estimates; but they must be kept in mind. Failure contains a probabilistic signal that maybe you should focus on something at least slightly different, and underaccounting for it can be as problematic as overaccounting for it.

    1. I agree. So there are two variables. One is the direction you are headed, and the other one is the energy you are expending. You want to change direction when needed, but you don’t want to lower your energy. It is one thing to work around obstacles, to redirect your energy… it is another to give up.

  6. I love how the scientific community trys to lump all ‘female’ or ‘male’ experiences into one field.

    As if human being experiences aren’t completely unique to all other.
    You are male: therefore :
    You are female: therefore :
    Can we stop thinking in binary terms for once?
    Humans are not, true, or false.
    Hell a rat, is not true or false. An atom is not true or false.
    Let’s not limit everything because we are limited.

    1. It seems that you don’t grasp that statistics works, no matter if you like it or not. We are unique (or we want to believe that), but we also follow some patterns. As rats do. And those patterns can be studied and, sometimes, predicted. Have you heard about marketing? It works because we follow some patterns of behavior. So, what’s the point of your comment, apart from showing no understanding of what “humans”, “males” or “females” words means in studies?

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